Author: Dr. Harrison Pidgeon Background: TXA, or tranexamic acid, has been used for everything from traumatic hemorrhage and post-partum bleeding to post tonsillectomy bleeding and angioedema. But what about for GI bleeding? TXA can bind to a lysine binding site on plasminogen which can stabilize and prevent break down of clots. So this should, in…
Author: Dr. Catherine Buckley Based on a simulation case discussion led by Dr. Michelle Hughes, let’s talk about Cystic fibrosis (CF) from an emergency medicine stand point. Briefly- CF is an autosomal recessive disease that is caused by mutations in the CFTR channel which prevents Cl- from being secreted. Without the normal levels of Cl-,…
All right folks, the chief complaint we all know and love: “rectal bleeding”. It may strike fear in your heart or bring you comfort in its algorithmic approach. However, GI bleeds can present in a variety of ways from the “sick” to “not sick”. So, grab your GUAIAC cards and let’s get started. UPPER GI…
Author: Dr. William Slagle Article: Nasogastric Aspiration and Lavage in Emergency Department Patients With Hematochezia or Melena Without Hematemesis Background: This is a paper about GI bleeds and what we should do for them in the ED. GI bleeding can range from mild to severe and can originate from anywhere in the GI tract. This…
Patients who have a history of IBD: chronic abdominal pain, diarrhea, fever, weightloss; coming into the emergency department for these same symptoms; how do we handle chronic disease in the emergency department?
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