5 Minute Journal: Smelling Salts not included

Dr. Harrison Pidgeon Background: We see nausea all the time in the Emergency Department (ED). Providers have different preferences on what agents they use as anti-emetics. But when put through the best evidence based tests (randomized controlled trials), ondansetron/Zofran, metoclopramide/Reglan, and prochlorperazine/Compazine fail to prove better than placebo for undifferentiated nausea. These agents are used

5 Minute Journal: Steroids and Antiviral Treatment for Bell’s Palsy

“Combined Corticosteroid and Antiviral Treatment for Bell’s Palsy A Systematic Review and Meta-analysis” Background/Study Question This article aimed to answer the question: Do steroids PLUS antivirals offer reduced risk of unsatisfactory facial recovery in patients with Bell’s Palsy? A little background about Bell’s Palsy; it is a cranial nerve 7 palsy thought to be viral

5 Minute Journal: Second Antibiotic Delays in Sepsis

Author: Dr. Tisma Background/Study Question How often do septic patients receive their second antibiotic dose later than they should? What are the risk factors for these delays? And do these delays affect patient outcomes? Leisman et. al. published a study in 2017 that examined these important inquiries. These questions are particularly interesting to me as

5 minute Journal: Hydrocortisone + Fludrocortisone for adults with septic shock

Author: Vanessa I. Petrak, M.D. Background: Septic Shock is a dysregulated host response to infection, resulting in life-threatening circulatory, cellular, and metabolic abnormalities. Sepsis is associated with a dysregulated response of the hypothalamic-pituitary-adrenal axis that may involve any of the steps from cortisol production to cortisol use by cells. Short term mortality is approximately 45-50%, and

5 minute Journal: Shocking Norepi Use

Author: Dr. Collin Wulff, DO Study Question: Does early low-dose norepinephrine improve shock control in those with sepsis with hypotension? Design: Mostly good buzzwords here; single center, randomized, double-blind, placebo controlled clinical trial, smallish study (310 total). The study group received a fairly low dose of norepi infusion (0.05 mcg/kg/min). The primary outcome was not

New Kid on The HyperK Block… Lokelma

Lokelma (Zirconium Cyclosilicate) I’m sure everyone has seen our new friend, Lokelma, on the Rush hyperkalemia order set. Thought it would be fun to do a blog post to discuss our new medication. Also have quick blurbs about our friend, Kayexalate, as well as a small summary on Veltassa (Patiromer) that you may see used

5 Minute Journal: Migraine Cocktail — over IV fluids or neat?

Author: Dr. Calloway Pichette Article: IV Fluids for the treatment of Emergency Department patients with migraine headache: a randomized controlled trial  Background: Headache, a common complaint in the ED. Many times a day we see patients with migraine headaches in the ED. Give them a migraine cocktail (sadly, no martinis involved…) and then viola! They